Crofelemer

A proprietary gastro-intestinal compound in clinical development for four distinct product indications

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news

July 1, 2008
Total Voting Rights and Share Capital

June 27, 2008
Issuance of US$0.12 Million Convertible Notes

June 23, 2008
US $2.1 million fundraising and update on partnership discussions

May 9, 2008
Napo presents at ISPOR meeting in Toronto

May 7, 2008
Napo RSA Announcement

May 7, 2008
Share Purchase

April 30, 2008
Napo Pharmaceuticals, Inc. 2007 Annual Report

April 30, 2008
Napo Annual Report and Accounts

April 25, 2008
Share Purchases

April 24, 2008
Share Purchase

April 21, 2008
Share Purchase

April 21, 2008
Interim Management Statement

April 17, 2008
Results for the Year Ended 31 December 2007

April 10, 2008
Napo Announces Successful Clinical Results in Phase 2 Study of Crofelemer in Acute Adult Infectious Diarrhea

March 13, 2008
Admission to CREST

March 5, 2008
$2.55 Million Fundraising by Way of Issue of Convertible Debt and Common Shares and $1.5 million Extension of Payment Terms with Certain Trade contractors

February 28, 2008
Napo Licenses Patent from University of Iowa Research Foundation for Secretory Diarrhea

February 19, 2008
Block Listing Six Monthly Return

February 11, 2008
Termination of Trine Agreement
Napo now in active discussions for commercial partner for crofelemer

February 6, 2008
Napo Receives Enteric Coated Formulation of Crofelemer Patent from United States Patent Office

February 4, 2008
Napo Appoints Dr. Jerome Ernst as Clinical Science Advisor

January 7, 2008
Issue of Convertible Promissory Notes

December 4, 2007
Glenmark Initiates Phase 2 Trial for Crofelemer for Acute Infectious Diarrhea

November 14, 2007
Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons

October 22. 2007
New Subs and Take Up of Funds Announcement

October 22. 2007
Annual Meeting Results

September 28, 2007
Placing and Subscription, Potential Further issue of Indicated Funds, Proposed Acquisition of Indus Pharmaceuticals, Inc and Block Listing of Shares

September 28, 2007
Interim Results for the Six Months Ended 30 June 2007

August 16, 2007
Napo Licenses CFTR Patents and Technology

July 30, 2007
Appointment of VP Regulatory Affairs and Quality Assurance

July 20, 2007
Transaction in Own Shares

July 3, 2007
Napo Obtains Special Protocol Assessment Agreement from FDA for Crofelemer in HIV/AIDS Diarrhea Assessment

June 28, 2007
Napo Pharmaceuticals, Inc. 2006 Annual Report

June 15, 2007
Final Audited Results for the year ended December 31 2006- Reduction of Non-cash Stock-Based Compensation from Previously Released Preliminary Results

June 14, 2007
Updated Statement of Total Voting Rights and Share Capital

June 12, 2007
Appointment of Thomas Van Dyck as Non-Executive Director

May 23, 2007
Phase 2a Diarrhea Predominant Irritable Bowel Syndrome Results from 2006 Presented at Digestive Disease Week in Washington D.C.

May 21, 2007
Ethics Committee Approval Granted for Multiple- Dose Continuation of Phase 2 Clinical Trial of Crofelemer for Treatment of Secretory Diarrhea Associated with Cholera Infection

May 15, 2007
Napo Confirms Satisfaction of Conditions of Conditional Private Placement of Common Shares

April 23, 2007
Napo Pharmaceuticals, Inc. Announces Board Changes

April 20, 2007
Proposed Board Changes

April 19, 2007
Napo Appointment and Removal of Directors and the Calling of an Extraordinary General Meeting

March 30, 2007
Preliminary Results for the Year Ended 31 December 2006

March 14, 2007
Napo Obtains IRB Approval for Phase 3 Clinical Trial Protocol for Crofelemer in HIV/AIDS Diarrhea Assessment

March 6, 2007
Appointment of Jack Van Hulst as Non-Executive Director

February 15, 2007
Postive Progress with Cholera Clinical Trial for Treatment of Secretory Diarrhea Associated with Cholera Infection

January 22, 2007
Collaboration with Nicholas Piramal

January 19, 2007
Updated Statement of Total Voting Rights

January 18, 2007
Transaction in Own Shares

January 12, 2007
Notification of Transactions

January 12, 2007
Appointment of COO

January 10, 2007
Application for Admission

January 10, 2007
Appointment of Board Member

January 8, 2007
Napo Receives Commitments for a Private Placement of Common Shares and Enters into Binding Letter of Intent for Intellectual Property License

December 21, 2006
Total Voting Rights and Share Capital

December 20, 2006
Napo Completes Feasibility Assessment

December 1, 2006
Block Listing of Shares - Further Clarification

December 1, 2006
Block Listing of Shares

November 17, 2006
Napo Announces Successful Production of Crofelemer

November 8, 2006
Appointment of VP Clinical Affairs and Chief Medical Officer

November 2, 2006
Appointment of VP Program Planning and Management

October 30, 2006
Trine Initiates Phase 2b Trial for D-IBS
Napo to Receive $1 million Milestone Payment

September 29, 2006
Napo Issued Share Capital September 29, 2006

September 28, 2006
Napo Issued Share Capital September 28, 2006

September 15, 2006
Interim Results for the Six Months ended June 30, 2006

August 3, 2006
Napo Pharmaceuticals, Inc. Receives Approval From Indian Regulator To Initiate Phase II Clinical Trial For Crofelemer For Acute Infectious Diarrhea In Adult Patients

August 2, 2006
London Stock Exchange Welcomes First Us-Incorporated Company To IPO On The Main Market

July 31, 2006
Napo Pharmaceuticals, Inc. admitted to trading on the Main Market of the London Stock Exchange

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